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Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

Cancer cells are known to execute reprogramed metabolism of glucose, amino acids and lipids. Here, we report a significant role of cholesterol metabolism in cancer metastasis. By using label-free Raman spectromicroscopy, we found an aberrant accumulation of cholesteryl ester in human pancreatic canc...

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Detalles Bibliográficos
Autores principales:	Li, J, Gu, D, Lee, S S-Y, Song, B, Bandyopadhyay, S, Chen, S, Konieczny, S F, Ratliff, T L, Liu, X, Xie, J, Cheng, J-X
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093084/ https://www.ncbi.nlm.nih.gov/pubmed/27132508 http://dx.doi.org/10.1038/onc.2016.168

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