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A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer

A high rate of aerobic glycolysis is a hallmark of malignant transformation. Accumulating evidence suggests that diverse regulatory mechanisms mediate this cancer-associated metabolic change seen in a wide spectrum of cancer. The echinoderm microtubule associated protein-like 4-anaplastic lymphoma k...

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Detalles Bibliográficos
Autores principales:	Ma, Yibao, Yu, Chunrong, Mohamed, Esraa M., Shao, Huanjie, Wang, Li, Sundaresan, Gobalakrishnan, Zweit, Jamal, Idowu, Michael, Fang, Xianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093092/ https://www.ncbi.nlm.nih.gov/pubmed/27132509 http://dx.doi.org/10.1038/onc.2016.150

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