Helicobacter pylori overcomes natural immunity in repeated infections

Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly...

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Detalles Bibliográficos
Autores principales: Stenström, Björn, Windsor, Helen M., Fulurija, Alma, Benghezal, Mohammed, Kumarasinghe, M. Priyanthi, Kimura, Kazufumi, Tay, Chin Yen, Viiala, Charlie H., Ee, Hooi C., Lu, Wei, Schoep, Tobias D., Webberley, K. Mary, Marshall, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093156/
https://www.ncbi.nlm.nih.gov/pubmed/27830066
http://dx.doi.org/10.1002/ccr3.687
Descripción
Sumario:Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines.

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