Helicobacter pylori overcomes natural immunity in repeated infections

Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly...

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Autores principales: Stenström, Björn, Windsor, Helen M., Fulurija, Alma, Benghezal, Mohammed, Kumarasinghe, M. Priyanthi, Kimura, Kazufumi, Tay, Chin Yen, Viiala, Charlie H., Ee, Hooi C., Lu, Wei, Schoep, Tobias D., Webberley, K. Mary, Marshall, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093156/
https://www.ncbi.nlm.nih.gov/pubmed/27830066
http://dx.doi.org/10.1002/ccr3.687
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author Stenström, Björn
Windsor, Helen M.
Fulurija, Alma
Benghezal, Mohammed
Kumarasinghe, M. Priyanthi
Kimura, Kazufumi
Tay, Chin Yen
Viiala, Charlie H.
Ee, Hooi C.
Lu, Wei
Schoep, Tobias D.
Webberley, K. Mary
Marshall, Barry J.
author_facet Stenström, Björn
Windsor, Helen M.
Fulurija, Alma
Benghezal, Mohammed
Kumarasinghe, M. Priyanthi
Kimura, Kazufumi
Tay, Chin Yen
Viiala, Charlie H.
Ee, Hooi C.
Lu, Wei
Schoep, Tobias D.
Webberley, K. Mary
Marshall, Barry J.
author_sort Stenström, Björn
collection PubMed
description Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines.
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spelling pubmed-50931562016-11-09 Helicobacter pylori overcomes natural immunity in repeated infections Stenström, Björn Windsor, Helen M. Fulurija, Alma Benghezal, Mohammed Kumarasinghe, M. Priyanthi Kimura, Kazufumi Tay, Chin Yen Viiala, Charlie H. Ee, Hooi C. Lu, Wei Schoep, Tobias D. Webberley, K. Mary Marshall, Barry J. Clin Case Rep Case Reports Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines. John Wiley and Sons Inc. 2016-09-23 /pmc/articles/PMC5093156/ /pubmed/27830066 http://dx.doi.org/10.1002/ccr3.687 Text en © 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Stenström, Björn
Windsor, Helen M.
Fulurija, Alma
Benghezal, Mohammed
Kumarasinghe, M. Priyanthi
Kimura, Kazufumi
Tay, Chin Yen
Viiala, Charlie H.
Ee, Hooi C.
Lu, Wei
Schoep, Tobias D.
Webberley, K. Mary
Marshall, Barry J.
Helicobacter pylori overcomes natural immunity in repeated infections
title Helicobacter pylori overcomes natural immunity in repeated infections
title_full Helicobacter pylori overcomes natural immunity in repeated infections
title_fullStr Helicobacter pylori overcomes natural immunity in repeated infections
title_full_unstemmed Helicobacter pylori overcomes natural immunity in repeated infections
title_short Helicobacter pylori overcomes natural immunity in repeated infections
title_sort helicobacter pylori overcomes natural immunity in repeated infections
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093156/
https://www.ncbi.nlm.nih.gov/pubmed/27830066
http://dx.doi.org/10.1002/ccr3.687
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