Diagnosis of a rare primary pulmonary synovial sarcoma with endobronchial ultrasound‐guided transbronchial needle aspiration

Primary pulmonary synovial sarcoma (PPSS) is a rare disease. Diagnosis is made postoperatively following resection of the tumor. We describe the case of a 39‐year‐old non‐smoking woman whose chest imaging revealed a heterogeneous mass (5.4 cm × 4.6 cm), with soft tissue density in the right upper lobe and pleural effusion in the right hemithorax. The tumor was enhanced on a computed tomography scan, in which enlargement of the mediastinal lymph nodes compressing the adjacent superior vena cava was observed. Endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) was then performed, which demonstrated PPSS, subsequently confirmed by immunohistochemistry and the detection of a SYT‐SSX fusion gene. We believe that a diagnostic approach of EBUS‐TBNA for lung sarcoma would provide helpful information to clinicians.