All-trans retinoic acid as adjunct to intensive treatment in younger adult patients with acute myeloid leukemia: results of the randomized AMLSG 07-04 study

The aim of this clinical trial was to evaluate the impact of all-trans retinoic acid (ATRA) in combination with chemotherapy and to assess the NPM1 status as biomarker for ATRA therapy in younger adult patients (18–60 years) with acute myeloid leukemia (AML). Patients were randomized for intensive c...

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Autores principales: Schlenk, Richard F., Lübbert, Michael, Benner, Axel, Lamparter, Alexander, Krauter, Jürgen, Herr, Wolfgang, Martin, Hans, Salih, Helmut R., Kündgen, Andrea, Horst, Heinz-A., Brossart, Peter, Götze, Katharina, Nachbaur, David, Wattad, Mohammed, Köhne, Claus-Henning, Fiedler, Walter, Bentz, Martin, Wulf, Gerald, Held, Gerhard, Hertenstein, Bernd, Salwender, Hans, Gaidzik, Verena I, Schlegelberger, Brigitte, Weber, Daniela, Döhner, Konstanze, Ganser, Arnold, Döhner, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093206/
https://www.ncbi.nlm.nih.gov/pubmed/27696203
http://dx.doi.org/10.1007/s00277-016-2810-z

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