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The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review

Cancer is currently a leading cause of deaths worldwide and the number of new cases is growing rapidly in both, developed and developing countries. Nutritional management during and after cancer treatment affects treatment efficacy and patient quality of life (QOL). This review systemically examined...

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Autores principales: Kim, Jin-Min, Sung, Mi-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Clinical Nutrition 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093220/
https://www.ncbi.nlm.nih.gov/pubmed/27812512
http://dx.doi.org/10.7762/cnr.2016.5.4.219
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author Kim, Jin-Min
Sung, Mi-Kyung
author_facet Kim, Jin-Min
Sung, Mi-Kyung
author_sort Kim, Jin-Min
collection PubMed
description Cancer is currently a leading cause of deaths worldwide and the number of new cases is growing rapidly in both, developed and developing countries. Nutritional management during and after cancer treatment affects treatment efficacy and patient quality of life (QOL). This review systemically examined the effect of oral nutritional interventions on nutritional and clinical outcomes in cancer patients. We especially focused on outcomes such as nutritional status indices, immune-associated biochemical markers, and QOL assessments to provide insights on the applicability of different outcomes. A total of 28 papers were selected for systematic review. The nutritional composition of oral nutritional supplements (ONS), outcome measures, and efficacy of the oral nutritional interventions were summarized and discussed. Most ONS contain 1 or more functional components in addition to basic nutrients. Each study used various outcome measures and significant efficacy was observed for a limited number of measures. Nutritional status indices, QOL measures, and the duration of hospital stay improved in about 40% of the studies. One or more markers of immune function and inflammatory responses were improved by ONS in 65% of the selected studies. These results suggest that appropriate use of ONS may be an ideal way to improve treatment efficacy; however, additional intervention trials are required to confirm these findings.
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spelling pubmed-50932202016-11-03 The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review Kim, Jin-Min Sung, Mi-Kyung Clin Nutr Res Review Article Cancer is currently a leading cause of deaths worldwide and the number of new cases is growing rapidly in both, developed and developing countries. Nutritional management during and after cancer treatment affects treatment efficacy and patient quality of life (QOL). This review systemically examined the effect of oral nutritional interventions on nutritional and clinical outcomes in cancer patients. We especially focused on outcomes such as nutritional status indices, immune-associated biochemical markers, and QOL assessments to provide insights on the applicability of different outcomes. A total of 28 papers were selected for systematic review. The nutritional composition of oral nutritional supplements (ONS), outcome measures, and efficacy of the oral nutritional interventions were summarized and discussed. Most ONS contain 1 or more functional components in addition to basic nutrients. Each study used various outcome measures and significant efficacy was observed for a limited number of measures. Nutritional status indices, QOL measures, and the duration of hospital stay improved in about 40% of the studies. One or more markers of immune function and inflammatory responses were improved by ONS in 65% of the selected studies. These results suggest that appropriate use of ONS may be an ideal way to improve treatment efficacy; however, additional intervention trials are required to confirm these findings. Korean Society of Clinical Nutrition 2016-10 2016-10-31 /pmc/articles/PMC5093220/ /pubmed/27812512 http://dx.doi.org/10.7762/cnr.2016.5.4.219 Text en Copyright © 2016 The Korean Society of Clinical Nutrition http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kim, Jin-Min
Sung, Mi-Kyung
The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review
title The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review
title_full The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review
title_fullStr The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review
title_full_unstemmed The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review
title_short The Efficacy of Oral Nutritional Intervention in Malnourished Cancer Patients: a Systemic Review
title_sort efficacy of oral nutritional intervention in malnourished cancer patients: a systemic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093220/
https://www.ncbi.nlm.nih.gov/pubmed/27812512
http://dx.doi.org/10.7762/cnr.2016.5.4.219
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