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Replication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1

Cells have evolved mechanisms to protect, restart and repair perturbed replication forks, allowing full genome duplication, even under replication stress. Interrogating the interplay between nuclease-helicase Dna2 and Holliday junction (HJ) resolvase Yen1, we find the Dna2 helicase activity acts par...

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Detalles Bibliográficos
Autores principales:	Ölmezer, Gizem, Levikova, Maryna, Klein, Dominique, Falquet, Benoît, Fontana, Gabriele Alessandro, Cejka, Petr, Rass, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093310/ https://www.ncbi.nlm.nih.gov/pubmed/27779184 http://dx.doi.org/10.1038/ncomms13157

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