Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment

The inbred mouse strain C57BL/6J is widely used in models of immunological and infectious diseases. Here we show that C57BL/6J mice have a defect in neutrophil recruitment to a range of inflammatory stimuli compared with the related C57BL/6N substrain. This immune perturbation is associated with a m...

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Detalles Bibliográficos
Autores principales: Ulland, Tyler K., Jain, Nidhi, Hornick, Emma E., Elliott, Eric I., Clay, Gwendolyn M., Sadler, Jeffrey J., Mills, Kathleen A. M., Janowski, Ann M., Volk, A. Paige Davis, Wang, Kai, Legge, Kevin L., Gakhar, Lokesh, Bourdi, Mohammed, Ferguson, Polly J., Wilson, Mary E., Cassel, Suzanne L., Sutterwala, Fayyaz S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093323/
https://www.ncbi.nlm.nih.gov/pubmed/27779193
http://dx.doi.org/10.1038/ncomms13180

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