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Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model

Aberrant iron deposition in the brain is associated with neurodegenerative disorders including Multiple Sclerosis, Alzheimer’s disease and Parkinson’s disease. To study the collective response to iron loading, we have used hippocampal organotypic slices as a platform to develop a novel ex vivo model...

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Detalles Bibliográficos
Autores principales: Healy, Sinead, McMahon, Jill, Owens, Peter, FitzGerald, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093415/
https://www.ncbi.nlm.nih.gov/pubmed/27808258
http://dx.doi.org/10.1038/srep36410