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Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model
Aberrant iron deposition in the brain is associated with neurodegenerative disorders including Multiple Sclerosis, Alzheimer’s disease and Parkinson’s disease. To study the collective response to iron loading, we have used hippocampal organotypic slices as a platform to develop a novel ex vivo model...
Autores principales: | Healy, Sinead, McMahon, Jill, Owens, Peter, FitzGerald, Una |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093415/ https://www.ncbi.nlm.nih.gov/pubmed/27808258 http://dx.doi.org/10.1038/srep36410 |
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