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mTORC1 inhibitor rapamycin and ER stressor tunicamycin induce differential patterns of ER-mitochondria coupling
Efficient mitochondrial Ca(2+) uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca(2+) transfer increases during the early phase of ER stress induced by...
Autores principales: | Bravo-Sagua, Roberto, López-Crisosto, Camila, Parra, Valentina, Rodriguez-Peña, Marcelo, Rothermel, Beverly A., Quest, Andrew F.G., Lavandero, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093439/ https://www.ncbi.nlm.nih.gov/pubmed/27808250 http://dx.doi.org/10.1038/srep36394 |
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