C2-domain mediated nano-cluster formation increases calcium signaling efficiency

Conventional protein kinase Cs (cPKCs) are key signaling proteins for transducing intracellular Ca(2+) signals into downstream phosphorylation events. However, the lifetime of individual membrane-bound activated cPKCs is an order of magnitude shorter than the average time needed for target-protein p...

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Detalles Bibliográficos
Autores principales: Bonny, Mike, Hui, Xin, Schweizer, Julia, Kaestner, Lars, Zeug, André, Kruse, Karsten, Lipp, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093555/
https://www.ncbi.nlm.nih.gov/pubmed/27808106
http://dx.doi.org/10.1038/srep36028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093555/
https://www.ncbi.nlm.nih.gov/pubmed/27808106
http://dx.doi.org/10.1038/srep36028

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