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C2-domain mediated nano-cluster formation increases calcium signaling efficiency
Conventional protein kinase Cs (cPKCs) are key signaling proteins for transducing intracellular Ca(2+) signals into downstream phosphorylation events. However, the lifetime of individual membrane-bound activated cPKCs is an order of magnitude shorter than the average time needed for target-protein p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093555/ https://www.ncbi.nlm.nih.gov/pubmed/27808106 http://dx.doi.org/10.1038/srep36028 |