Cargando…
Functional variants of the 5-methyltetrahydrofolate-homocysteine methyltransferase gene significantly increase susceptibility to prostate cancer: Results from an ethnic Han Chinese population
Aberrant DNA methylation has been implicated in prostate carcinogenesis. The one-carbon metabolism pathway and related metabolites determine cellular DNA methylation and thus is thought to play a pivotal role in PCa occurrence. This study aimed to investigate the contribution of genetic variants in...
Autores principales: | Qu, Yuan-Yuan, Zhou, Shu-Xian, Zhang, Xuan, Zhao, Rui, Gu, Cheng-Yuan, Chang, Kun, Yang, Xiao-Qun, Gan, Hua-Lei, Dai, Bo, Zhang, Hai-Liang, Shi, Guo-Hai, Zhu, Yao, Ye, Ding-Wei, Zhao, Jian-Yuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093691/ https://www.ncbi.nlm.nih.gov/pubmed/27808252 http://dx.doi.org/10.1038/srep36264 |
Ejemplares similares
-
MTHFR c.677C>T Inhibits Cell Proliferation and Decreases Prostate Cancer Susceptibility in the Han Chinese Population in Shanghai
por: Wu, Jun-Long, et al.
Publicado: (2016) -
Effects of Periconceptional Multivitamin Supplementation on Folate and Homocysteine Levels Depending on Genetic Variants of Methyltetrahydrofolate Reductase in Infertile Japanese Women
por: Kuroda, Keiji, et al.
Publicado: (2021) -
Homocysteine Homeostasis and Betaine-Homocysteine S-Methyltransferase Expression in the Brain of Hibernating Bats
por: Zhang, Yijian, et al.
Publicado: (2013) -
Simultaneous quantitation of folic acid and 5-methyltetrahydrofolic acid in human plasma by HPLC–MS/MS and its application to a pharmacokinetic study()
por: Zheng, Xiao-Hong, et al.
Publicado: (2015) -
Association between serum 5-methyltetrahydrofolate and homocysteine in Chinese hypertensive participants with different MTHFR C677T polymorphisms: a cross-sectional study
por: Cheng, Yu, et al.
Publicado: (2022)