Ryanodine-induced vasoconstriction of the gerbil spiral modiolar artery depends on the Ca(2+) sensitivity but not on Ca(2+) sparks or BK channels

BACKGROUND: In many vascular smooth muscle cells (SMCs), ryanodine receptor-mediated Ca(2+) sparks activate large-conductance Ca(2+)-activated K(+) (BK) channels leading to lowered SMC [Ca(2+)](i) and vasodilation. Here we investigated whether Ca(2+) sparks regulate SMC global [Ca(2+)](i) and diamet...

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Detalles Bibliográficos
Autores principales: Krishnamoorthy, Gayathri, Reimann, Katrin, Wangemann, Philine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093982/
https://www.ncbi.nlm.nih.gov/pubmed/27806708
http://dx.doi.org/10.1186/s12899-016-0026-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093982/
https://www.ncbi.nlm.nih.gov/pubmed/27806708
http://dx.doi.org/10.1186/s12899-016-0026-z

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