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Ryanodine-induced vasoconstriction of the gerbil spiral modiolar artery depends on the Ca(2+) sensitivity but not on Ca(2+) sparks or BK channels
BACKGROUND: In many vascular smooth muscle cells (SMCs), ryanodine receptor-mediated Ca(2+) sparks activate large-conductance Ca(2+)-activated K(+) (BK) channels leading to lowered SMC [Ca(2+)](i) and vasodilation. Here we investigated whether Ca(2+) sparks regulate SMC global [Ca(2+)](i) and diamet...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093982/ https://www.ncbi.nlm.nih.gov/pubmed/27806708 http://dx.doi.org/10.1186/s12899-016-0026-z |