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Leveraging genetically simple traits to identify small-effect variants for complex phenotypes

BACKGROUND: Polymorphisms underlying complex traits often explain a small part (less than 1 %) of the phenotypic variance (σ(2) (P)). This makes identification of mutations underling complex traits difficult and usually only a subset of large-effect loci are identified. One approach to identify more...

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Detalles Bibliográficos
Autores principales:	Kemper, K. E., Littlejohn, M. D., Lopdell, T., Hayes, B. J., Bennett, L. E., Williams, R. P., Xu, X. Q., Visscher, P. M., Carrick, M. J., Goddard, M. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094043/ https://www.ncbi.nlm.nih.gov/pubmed/27809761 http://dx.doi.org/10.1186/s12864-016-3175-3

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