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Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V

There are few published reports of mutations in dihydropteroate synthetase (dhps) and dihydrofolate reductase (dhfr) genes in P. falciparum populations in Nigeria, but one previous study has recorded a novel dhps mutation at codon 431 among infections imported to the United Kingdom from Nigeria. To...

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Detalles Bibliográficos
Autores principales: Oguike, Mary C., Falade, Catherine O., Shu, Elvis, Enato, Izehiuwa G., Watila, Ismaila, Baba, Ebenezer S., Bruce, Jane, Webster, Jayne, Hamade, Prudence, Meek, Sylvia, Chandramohan, Daniel, Sutherland, Colin J., Warhurst, David, Roper, Cally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094156/
https://www.ncbi.nlm.nih.gov/pubmed/27821281
http://dx.doi.org/10.1016/j.ijpddr.2016.08.004

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