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Primary age-related tauopathy and the amyloid cascade hypothesis: the exception that proves the rule?
Extensive data supports the amyloid cascade hypothesis, which states that Alzheimer’s disease (AD) stems from neurotoxic forms of the amyloid-beta (Aβ) peptide. But the poor correlation between Aβ plaques and neurodegeneration/cognitive impairment, the spaciotemporal disparity between Aβ and tau pat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094182/ https://www.ncbi.nlm.nih.gov/pubmed/27819070 |