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Microglia and neuroinflammation: a pathological perspective
Microglia make up the innate immune system of the central nervous system and are key cellular mediators of neuroinflammatory processes. Their role in central nervous system diseases, including infections, is discussed in terms of a participation in both acute and chronic neuroinflammatory responses....
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509427/ https://www.ncbi.nlm.nih.gov/pubmed/15285801 http://dx.doi.org/10.1186/1742-2094-1-14 |
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| author | Streit, Wolfgang J Mrak, Robert E Griffin, W Sue T |
| author_facet | Streit, Wolfgang J Mrak, Robert E Griffin, W Sue T |
| author_sort | Streit, Wolfgang J |
| collection | PubMed |
| description | Microglia make up the innate immune system of the central nervous system and are key cellular mediators of neuroinflammatory processes. Their role in central nervous system diseases, including infections, is discussed in terms of a participation in both acute and chronic neuroinflammatory responses. Specific reference is made also to their involvement in Alzheimer's disease where microglial cell activation is thought to be critically important in the neurodegenerative process. |
| format | Text |
| id | pubmed-509427 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2004 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-5094272004-08-15 Microglia and neuroinflammation: a pathological perspective Streit, Wolfgang J Mrak, Robert E Griffin, W Sue T J Neuroinflammation Review Microglia make up the innate immune system of the central nervous system and are key cellular mediators of neuroinflammatory processes. Their role in central nervous system diseases, including infections, is discussed in terms of a participation in both acute and chronic neuroinflammatory responses. Specific reference is made also to their involvement in Alzheimer's disease where microglial cell activation is thought to be critically important in the neurodegenerative process. BioMed Central 2004-07-30 /pmc/articles/PMC509427/ /pubmed/15285801 http://dx.doi.org/10.1186/1742-2094-1-14 Text en Copyright © 2004 Streit et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Review Streit, Wolfgang J Mrak, Robert E Griffin, W Sue T Microglia and neuroinflammation: a pathological perspective |
| title | Microglia and neuroinflammation: a pathological perspective |
| title_full | Microglia and neuroinflammation: a pathological perspective |
| title_fullStr | Microglia and neuroinflammation: a pathological perspective |
| title_full_unstemmed | Microglia and neuroinflammation: a pathological perspective |
| title_short | Microglia and neuroinflammation: a pathological perspective |
| title_sort | microglia and neuroinflammation: a pathological perspective |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC509427/ https://www.ncbi.nlm.nih.gov/pubmed/15285801 http://dx.doi.org/10.1186/1742-2094-1-14 |
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