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Abnormal coagulation tests before kidney biopsies—what next?

INTRODUCTION: Bleeding is one of the most feared risks from a renal biopsy. To determine this risk, a clotting screen is performed prior to the biopsy to identify any coagulation abnormalities. In addition, concerns exist with respect to bleeding from platelet dysfunction and the special cases of pa...

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Autor principal: Thachil, Jecko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094395/
https://www.ncbi.nlm.nih.gov/pubmed/27818751
http://dx.doi.org/10.1093/ckj/sfs163
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author Thachil, Jecko
author_facet Thachil, Jecko
author_sort Thachil, Jecko
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description INTRODUCTION: Bleeding is one of the most feared risks from a renal biopsy. To determine this risk, a clotting screen is performed prior to the biopsy to identify any coagulation abnormalities. In addition, concerns exist with respect to bleeding from platelet dysfunction and the special cases of paraprotenemia. METHOD: Literature search of all the relevant articles in relation to bleeding risk from clotting abnormalities and platelet dysfunction in the setting of kidney biopsy was conducted. RESULTS: Bleeding risk from abnormal clotting screen is minimal in the absence of prior bleeding history in patients with renal disease. Administration of fresh frozen plasma in these cases is probably unnecessary and often causes delay in the procedure. In a similar way, platelet transfusions may not be appropriate in those with platelet dysfunction. CONCLUSIONS: Global coagulation function tests are now available which need to be considered to determine bleeding risk before kidney biopsy, in conjunction with a good patient history.
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spelling pubmed-50943952016-11-04 Abnormal coagulation tests before kidney biopsies—what next? Thachil, Jecko Clin Kidney J Original Contributions INTRODUCTION: Bleeding is one of the most feared risks from a renal biopsy. To determine this risk, a clotting screen is performed prior to the biopsy to identify any coagulation abnormalities. In addition, concerns exist with respect to bleeding from platelet dysfunction and the special cases of paraprotenemia. METHOD: Literature search of all the relevant articles in relation to bleeding risk from clotting abnormalities and platelet dysfunction in the setting of kidney biopsy was conducted. RESULTS: Bleeding risk from abnormal clotting screen is minimal in the absence of prior bleeding history in patients with renal disease. Administration of fresh frozen plasma in these cases is probably unnecessary and often causes delay in the procedure. In a similar way, platelet transfusions may not be appropriate in those with platelet dysfunction. CONCLUSIONS: Global coagulation function tests are now available which need to be considered to determine bleeding risk before kidney biopsy, in conjunction with a good patient history. Oxford University Press 2013-02 2013-01-09 /pmc/articles/PMC5094395/ /pubmed/27818751 http://dx.doi.org/10.1093/ckj/sfs163 Text en © The Author 2013. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please email: journals.permissions@oup.com http://creativecommons.org/licenses/by-nc/4.0/ this is an open access article distributed under the terms of the creative commons attribution non-commercial license (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. for commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Contributions
Thachil, Jecko
Abnormal coagulation tests before kidney biopsies—what next?
title Abnormal coagulation tests before kidney biopsies—what next?
title_full Abnormal coagulation tests before kidney biopsies—what next?
title_fullStr Abnormal coagulation tests before kidney biopsies—what next?
title_full_unstemmed Abnormal coagulation tests before kidney biopsies—what next?
title_short Abnormal coagulation tests before kidney biopsies—what next?
title_sort abnormal coagulation tests before kidney biopsies—what next?
topic Original Contributions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094395/
https://www.ncbi.nlm.nih.gov/pubmed/27818751
http://dx.doi.org/10.1093/ckj/sfs163
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