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Effect of amlodipine, lisinopril and allopurinol on acetaminophen-induced hepatotoxicity in rats

BACKGROUND: Exposure to chemotherapeutic agents such as acetaminophen may lead to serious liver injury. Calcium deregulation, angiotensin II production and xanthine oxidase activity are suggested to play mechanistic roles in such injury. OBJECTIVE: This study evaluates the possible protective effect...

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Detalles Bibliográficos
Autores principales: Mohammed, Nesreen E.M., Messiha, Basim A.S., Abo-Saif, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094429/
https://www.ncbi.nlm.nih.gov/pubmed/27829805
http://dx.doi.org/10.1016/j.jsps.2015.04.004

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