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Effect of amlodipine, lisinopril and allopurinol on acetaminophen-induced hepatotoxicity in rats
BACKGROUND: Exposure to chemotherapeutic agents such as acetaminophen may lead to serious liver injury. Calcium deregulation, angiotensin II production and xanthine oxidase activity are suggested to play mechanistic roles in such injury. OBJECTIVE: This study evaluates the possible protective effect...
Autores principales: | Mohammed, Nesreen E.M., Messiha, Basim A.S., Abo-Saif, Ali A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094429/ https://www.ncbi.nlm.nih.gov/pubmed/27829805 http://dx.doi.org/10.1016/j.jsps.2015.04.004 |
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