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Effect of tramadol on metamizol pharmacokinetics and pharmacodynamics after single and repeated administrations in arthritic rats

Combined administration of certain doses of opioid compounds with a non-steroidal anti-inflammatory drug can produce additive or supra-additive effects while reducing unwanted effects. We have recently reported that co-administration of metamizol with tramadol produces antinociceptive effect potenti...

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Detalles Bibliográficos
Autores principales: Moreno-Rocha, Luis Alfonso, López-Muñoz, Francisco Javier, Medina-López, José Raúl, Domínguez-Ramírez, Adriana Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094430/
https://www.ncbi.nlm.nih.gov/pubmed/27829810
http://dx.doi.org/10.1016/j.jsps.2015.06.005

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