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Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization

A series of glycinate and carbonate derivatives of cholesterol (4a–t) were synthesized, characterized and assessed for their in vitro antimicrobial activity. Our results revealed that the compounds exerted inhibitory activities against gram-negative bacteria and fungi.

Detalles Bibliográficos
Autores principales: Sribalan, Rajendran, Padmini, Vediappen, Lavanya, Andiappan, Ponnuvel, Kandasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094438/
https://www.ncbi.nlm.nih.gov/pubmed/27829808
http://dx.doi.org/10.1016/j.jsps.2015.05.003
Descripción
Sumario:A series of glycinate and carbonate derivatives of cholesterol (4a–t) were synthesized, characterized and assessed for their in vitro antimicrobial activity. Our results revealed that the compounds exerted inhibitory activities against gram-negative bacteria and fungi.