Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization

A series of glycinate and carbonate derivatives of cholesterol (4a–t) were synthesized, characterized and assessed for their in vitro antimicrobial activity. Our results revealed that the compounds exerted inhibitory activities against gram-negative bacteria and fungi.

Detalles Bibliográficos
Autores principales: Sribalan, Rajendran, Padmini, Vediappen, Lavanya, Andiappan, Ponnuvel, Kandasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094438/
https://www.ncbi.nlm.nih.gov/pubmed/27829808
http://dx.doi.org/10.1016/j.jsps.2015.05.003
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author Sribalan, Rajendran
Padmini, Vediappen
Lavanya, Andiappan
Ponnuvel, Kandasamy
author_facet Sribalan, Rajendran
Padmini, Vediappen
Lavanya, Andiappan
Ponnuvel, Kandasamy
author_sort Sribalan, Rajendran
collection PubMed
description A series of glycinate and carbonate derivatives of cholesterol (4a–t) were synthesized, characterized and assessed for their in vitro antimicrobial activity. Our results revealed that the compounds exerted inhibitory activities against gram-negative bacteria and fungi.
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spelling pubmed-50944382016-11-09 Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization Sribalan, Rajendran Padmini, Vediappen Lavanya, Andiappan Ponnuvel, Kandasamy Saudi Pharm J Original Article A series of glycinate and carbonate derivatives of cholesterol (4a–t) were synthesized, characterized and assessed for their in vitro antimicrobial activity. Our results revealed that the compounds exerted inhibitory activities against gram-negative bacteria and fungi. Elsevier 2016-11 2015-06-01 /pmc/articles/PMC5094438/ /pubmed/27829808 http://dx.doi.org/10.1016/j.jsps.2015.05.003 Text en © 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Sribalan, Rajendran
Padmini, Vediappen
Lavanya, Andiappan
Ponnuvel, Kandasamy
Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization
title Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization
title_full Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization
title_fullStr Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization
title_full_unstemmed Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization
title_short Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization
title_sort evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: synthesis and characterization
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094438/
https://www.ncbi.nlm.nih.gov/pubmed/27829808
http://dx.doi.org/10.1016/j.jsps.2015.05.003
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AT lavanyaandiappan evaluationofantimicrobialactivityofglycinateandcarbonatederivativesofcholesterolsynthesisandcharacterization
AT ponnuvelkandasamy evaluationofantimicrobialactivityofglycinateandcarbonatederivativesofcholesterolsynthesisandcharacterization

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