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Electrostatics and Intrinsic Disorder Drive Translocon Binding of the SRP Receptor FtsY

Integral membrane proteins in bacteria are co‐translationally targeted to the SecYEG translocon for membrane insertion via the signal recognition particle (SRP) pathway. The SRP receptor FtsY and its N‐terminal A domain, which is lacking in any structural model of FtsY, were studied using NMR and fl...

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Detalles Bibliográficos
Autores principales: Lakomek, Nils‐Alexander, Draycheva, Albena, Bornemann, Thomas, Wintermeyer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094494/
https://www.ncbi.nlm.nih.gov/pubmed/27346853
http://dx.doi.org/10.1002/anie.201602905

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