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Electrostatics and Intrinsic Disorder Drive Translocon Binding of the SRP Receptor FtsY
Integral membrane proteins in bacteria are co‐translationally targeted to the SecYEG translocon for membrane insertion via the signal recognition particle (SRP) pathway. The SRP receptor FtsY and its N‐terminal A domain, which is lacking in any structural model of FtsY, were studied using NMR and fl...
Autores principales: | Lakomek, Nils‐Alexander, Draycheva, Albena, Bornemann, Thomas, Wintermeyer, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094494/ https://www.ncbi.nlm.nih.gov/pubmed/27346853 http://dx.doi.org/10.1002/anie.201602905 |
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