Cargando…

Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?

Type 2 diabetes mellitus (T2DM) is a major cause of cardiovascular (CV) disease. Several large clinical trials have shown that the risk for patients with diabetes of developing CV complications is only partially reduced by early, intensive glycaemic control and lifestyle interventions, and that such...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prattichizzo, F., Giuliani, A., De Nigris, V., Pujadas, G., Ceka, A., La Sala, L., Genovese, S., Testa, R., Procopio, A. D., Olivieri, F., Ceriello, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2016
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094499/ https://www.ncbi.nlm.nih.gov/pubmed/27161301 http://dx.doi.org/10.1111/dom.12688

Ejemplares similares

The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin functions as antioxidant on human endothelial cells exposed to chronic hyperglycemia and metabolic high-glucose memory
por: Pujadas, Gemma, et al.
Publicado: (2016)

Short-term high glucose exposure impairs insulin signaling in endothelial cells
por: De Nigris, Valeria, et al.
Publicado: (2015)

Epigenetic mechanisms of endothelial dysfunction in type 2 diabetes
por: Prattichizzo, Francesco, et al.
Publicado: (2015)

“Inflammaging” as a Druggable Target: A Senescence-Associated Secretory Phenotype—Centered View of Type 2 Diabetes
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its cardiovascular complications
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

Extracellular vesicles circulating in young organisms promote healthy longevity
por: Prattichizzo, Francesco, et al.
Publicado: (2019)

Teneligliptin enhances the beneficial effects of GLP-1 in endothelial cells exposed to hyperglycemic conditions
por: De Nigris, Valeria, et al.
Publicado: (2017)

Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells
por: La Sala, Lucia, et al.
Publicado: (2016)

The “Metabolic Memory” Theory and the Early Treatment of Hyperglycemia in Prevention of Diabetic Complications
por: Testa, Roberto, et al.
Publicado: (2017)

Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages
por: Prattichizzo, Francesco, et al.
Publicado: (2017)

The protective effect of the Mediterranean diet on endothelial resistance to GLP-1 in type 2 diabetes: a preliminary report
por: Ceriello, Antonio, et al.
Publicado: (2014)

GLP-1 reduces metalloproteinase-9 induced by both hyperglycemia and hypoglycemia in type 1 diabetes. The possible role of oxidative stress
por: Ceriello, Antonio, et al.
Publicado: (2015)

DPP-4 Inhibitors Have Different Effects on Endothelial Low-Grade Inflammation and on the M1-M2 Macrophage Polarization Under Hyperglycemic Conditions
por: De Nigris, Valeria, et al.
Publicado: (2021)

Where Metabolism Meets Senescence: Focus on Endothelial Cells
por: Sabbatinelli, Jacopo, et al.
Publicado: (2019)

Anti-TNF-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

Age- and glycemia-related miR-126-3p levels in plasma and endothelial cells
por: Olivieri, Fabiola, et al.
Publicado: (2014)

Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?
por: Giuliani, Angelica, et al.
Publicado: (2017)

Corrigendum to “Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?”
por: Giuliani, Angelica, et al.
Publicado: (2019)

Hyperglycaemic Hemichorea
por: Marques, Joana Silva, et al.
Publicado: (2018)

The Possible Role of Flavonoids in the Prevention of Diabetic Complications
por: Testa, Roberto, et al.
Publicado: (2016)

DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Glucagon-Like Peptide 1 Reduces Endothelial Dysfunction, Inflammation, and Oxidative Stress Induced by Both Hyperglycemia and Hypoglycemia in Type 1 Diabetes
por: Ceriello, Antonio, et al.
Publicado: (2013)

Vitamin C Further Improves the Protective Effect of Glucagon-Like Peptide-1 on Acute Hypoglycemia-Induced Oxidative Stress, Inflammation, and Endothelial Dysfunction in Type 1 Diabetes
por: Ceriello, Antonio, et al.
Publicado: (2013)

Citrate treatment reduces endothelial death and inflammation under hyperglycaemic conditions
por: Bryland, Anna, et al.
Publicado: (2012)

The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells
por: Giuliani, Angelica, et al.
Publicado: (2018)

Evidence That Hyperglycemia After Recovery From Hypoglycemia Worsens Endothelial Function and Increases Oxidative Stress and Inflammation in Healthy Control Subjects and Subjects With Type 1 Diabetes
por: Ceriello, Antonio, et al.
Publicado: (2012)

Long-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs
por: Giuliani, Angelica, et al.
Publicado: (2020)

Blood Co-Circulating Extracellular microRNAs and Immune Cell Subsets Associate with Type 1 Diabetes Severity
por: Garavelli, Silvia, et al.
Publicado: (2020)

Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
por: Mensà, Emanuela, et al.
Publicado: (2020)

Tackling the pillars of ageing to fight COVID-19
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

STRATEGIES FOR PREVENTION OF HYPERGLYCAEMIC EMERGENCIES IN NIGERIA
por: Balogun, WO, et al.
Publicado: (2008)

Fatal Hyperosmolar Hyperglycaemic Syndrome complicated by severe Rhabdomyolysis
por: Joseph, Amer, et al.
Publicado: (2012)

Hypoxia mimetics restore bone biomineralisation in hyperglycaemic environments
por: Rezaei, Azadeh, et al.
Publicado: (2022)

AZD-1222: Hyperglycaemic ketosis, mixed hyperglycaemic hypermolar state/diabetic ketoacidosis and diabetic ketoacidosis: 3 case reports
Publicado: (2021)

Corticosteroid induced hyperosmolar hyperglycaemic state and hemiballismus
por: Chinthapalli, Krishna, et al.
Publicado: (2015)

Spectrum of hyperosmolar hyperglycaemic state in neurology practice
por: Misra, U.K., et al.
Publicado: (2017)

Central Pontine Myelinolysis in the Hyperosmolar Hyperglycaemic State
por: Hegazi, Mohamed Osama, et al.
Publicado: (2012)

Incidence of hyperglycaemic disorders in children and adolescents with obesity
por: Chylińska-Frątczak, Aneta, et al.
Publicado: (2022)

Vitamin C further improves the protective effect of GLP-1 on the ischemia-reperfusion-like effect induced by hyperglycemia post-hypoglycemia in type 1 diabetes
por: Ceriello, Antonio, et al.
Publicado: (2013)

Melatonin suppresses the brain injury after cerebral ischemia/reperfusion in hyperglycaemic rats
por: Saleh, Dalia O., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ftrdjin76e6o5459mbus204ke1