Continuous‐Flow Synthesis and Derivatization of Aziridines through Palladium‐Catalyzed C(sp(3))−H Activation

A continuous‐flow synthesis of aziridines by palladium‐catalyzed C(sp(3))−H activation is described. The new flow reaction could be combined with an aziridine‐ring‐opening reaction to give highly functionalized aliphatic amines through a consecutive process. A predictive mechanistic model was develo...

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Detalles Bibliográficos
Autores principales: Zakrzewski, Jacek, Smalley, Adam P., Kabeshov, Mikhail A., Gaunt, Matthew J., Lapkin, Alexei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094502/
https://www.ncbi.nlm.nih.gov/pubmed/27304395
http://dx.doi.org/10.1002/anie.201602483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094502/
https://www.ncbi.nlm.nih.gov/pubmed/27304395
http://dx.doi.org/10.1002/anie.201602483

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