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Continuous‐Flow Synthesis and Derivatization of Aziridines through Palladium‐Catalyzed C(sp(3))−H Activation
A continuous‐flow synthesis of aziridines by palladium‐catalyzed C(sp(3))−H activation is described. The new flow reaction could be combined with an aziridine‐ring‐opening reaction to give highly functionalized aliphatic amines through a consecutive process. A predictive mechanistic model was develo...
Autores principales: | Zakrzewski, Jacek, Smalley, Adam P., Kabeshov, Mikhail A., Gaunt, Matthew J., Lapkin, Alexei A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094502/ https://www.ncbi.nlm.nih.gov/pubmed/27304395 http://dx.doi.org/10.1002/anie.201602483 |
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