In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti‐Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats

BACKGROUND: Limited options are available for the treatment of pain in cats. Monoclonal antibodies (mAbs) that neutralize nerve growth factor (NGF) have demonstrated analgesic capacity in rodent models, people with osteoarthritis, and dogs with degenerative joint disease. HYPOTHESIS/OBJECTIVES: This...

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Detalles Bibliográficos
Autores principales: Gearing, D.P., Huebner, M., Virtue, E.R., Knight, K., Hansen, P., Lascelles, B.D.X., Gearing, R.P., Drew, A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094543/
https://www.ncbi.nlm.nih.gov/pubmed/27306920
http://dx.doi.org/10.1111/jvim.13985

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