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High‐precision iRT prediction in the targeted analysis of data‐independent acquisition and its impact on identification and quantitation

Targeted analysis of data‐independent acquisition (DIA) data is a powerful mass spectrometric approach for comprehensive, reproducible and precise proteome quantitation. It requires a spectral library, which contains for all considered peptide precursor ions empirically determined fragment ion inten...

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Detalles Bibliográficos
Autores principales: Bruderer, Roland, Bernhardt, Oliver M., Gandhi, Tejas, Reiter, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094550/
https://www.ncbi.nlm.nih.gov/pubmed/27213465
http://dx.doi.org/10.1002/pmic.201500488