Peptide drugs accelerate BMP‐2‐induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling

Both W9 and OP3‐4 were known to bind the receptor activator of NF‐κB ligand (RANKL), inhibiting osteoclastogenesis. Recently, both peptides were shown to stimulate osteoblast differentiation; however, the mechanism underlying the activity of these peptides remains to be clarified. A primary osteobla...

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Detalles Bibliográficos
Autores principales: Sugamori, Yasutaka, Mise‐Omata, Setsuko, Maeda, Chizuko, Aoki, Shigeki, Tabata, Yasuhiko, Murali, Ramachandran, Yasuda, Hisataka, Udagawa, Nobuyuki, Suzuki, Hiroshi, Honma, Masashi, Aoki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094554/
https://www.ncbi.nlm.nih.gov/pubmed/27345003
http://dx.doi.org/10.1002/bies.201600104

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