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Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages
Obesity in humans and mice is typified by an activated macrophage phenotype in the visceral adipose tissue (VAT) leading to increased macrophage-mediated inflammation. microRNAs (miRNAs) play an important role in regulating inflammatory pathways in macrophages, and in this study we compared miRNA ex...
Autores principales: | Deiuliis, Jeffrey A., Syed, Rafay, Duggineni, Dheeraj, Rutsky, Jessica, Rengasamy, Palanivel, Zhang, Jie, Huang, Kun, Needleman, Bradley, Mikami, Dean, Perry, Kyle, Hazey, Jeffrey, Rajagopalan, Sanjay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094706/ https://www.ncbi.nlm.nih.gov/pubmed/27812198 http://dx.doi.org/10.1371/journal.pone.0165962 |
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