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Calcium Binding and Disulfide Bonds Regulate the Stability of Secretagogin towards Thermal and Urea Denaturation
Secretagogin is a calcium-sensor protein with six EF-hands. It is widely expressed in neurons and neuro-endocrine cells of a broad range of vertebrates including mammals, fishes and amphibia. The protein plays a role in secretion and interacts with several vesicle-associated proteins. In this work,...
Autores principales: | Sanagavarapu, Kalyani, Weiffert, Tanja, Ní Mhurchú, Niamh, O’Connell, David, Linse, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094748/ https://www.ncbi.nlm.nih.gov/pubmed/27812162 http://dx.doi.org/10.1371/journal.pone.0165709 |
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