Cathelicidin Insufficiency in Patients with Fatal Leptospirosis

Leptospirosis causes significant morbidity and mortality worldwide; however, the role of the host immune response in disease progression and high case fatality (>10–50%) is poorly understood. We conducted a multi-parameter investigation of patients with acute leptospirosis to identify mechanisms...

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Detalles Bibliográficos
Autores principales: Lindow, Janet C., Wunder, Elsio A., Popper, Stephen J., Min, Jin-na, Mannam, Praveen, Srivastava, Anup, Yao, Yi, Hacker, Kathryn P., Raddassi, Khadir, Lee, Patty J., Montgomery, Ruth R., Shaw, Albert C., Hagan, Jose E., Araújo, Guilherme C., Nery, Nivison, Relman, David A., Kim, Charles C., Reis, Mitermayer G., Ko, Albert I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094754/
https://www.ncbi.nlm.nih.gov/pubmed/27812211
http://dx.doi.org/10.1371/journal.ppat.1005943

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