The Human Mixed Lineage Leukemia 5 (MLL5), a Sequentially and Structurally Divergent SET Domain-Containing Protein with No Intrinsic Catalytic Activity

Mixed Lineage Leukemia 5 (MLL5) plays a key role in hematopoiesis, spermatogenesis and cell cycle progression. Chromatin binding is ensured by its plant homeodomain (PHD) through a direct interaction with the N-terminus of histone H3 (H3). In addition, MLL5 contains a Su(var)3-9, Enhancer of zeste,...

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Detalles Bibliográficos
Autores principales: Mas-y-Mas, Sarah, Barbon, Marta, Teyssier, Catherine, Déméné, Hélène, Carvalho, João E., Bird, Louise E., Lebedev, Andrey, Fattori, Juliana, Schubert, Michael, Dumas, Christian, Bourguet, William, le Maire, Albane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094779/
https://www.ncbi.nlm.nih.gov/pubmed/27812132
http://dx.doi.org/10.1371/journal.pone.0165139

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