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A Mutational Hotspot and Strong Selection Contribute to the Order of Mutations Selected for during Escherichia coli Adaptation to the Gut
The relative role of drift versus selection underlying the evolution of bacterial species within the gut microbiota remains poorly understood. The large sizes of bacterial populations in this environment suggest that even adaptive mutations with weak effects, thought to be the most frequently occurr...
Autores principales: | Lourenço, Marta, Ramiro, Ricardo S., Güleresi, Daniela, Barroso-Batista, João, Xavier, Karina B., Gordo, Isabel, Sousa, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094792/ https://www.ncbi.nlm.nih.gov/pubmed/27812114 http://dx.doi.org/10.1371/journal.pgen.1006420 |
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