Cargando…

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders

Numerous genetic variants associated with MEF2C are linked to autism, intellectual disability (ID) and schizophrenia (SCZ) – a heterogeneous collection of neurodevelopmental disorders with unclear pathophysiology. MEF2C is highly expressed in developing cortical excitatory neurons, but its role in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harrington, Adam J, Raissi, Aram, Rajkovich, Kacey, Berto, Stefano, Kumar, Jaswinder, Molinaro, Gemma, Raduazzo, Jonathan, Guo, Yuhong, Loerwald, Kris, Konopka, Genevieve, Huber, Kimberly M, Cowan, Christopher W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094851/ https://www.ncbi.nlm.nih.gov/pubmed/27779093 http://dx.doi.org/10.7554/eLife.20059

Ejemplares similares

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum
por: Araujo, Daniel J., et al.
Publicado: (2015)

Editorial: Latest Advances on Excitatory Synapse Biology
por: Huber, Kimberly M., et al.
Publicado: (2021)

An essential role for MEF2C in the cortical response to loss of sleep in mice
por: Bjorness, Theresa E, et al.
Publicado: (2020)

NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress-induced anhedonia-like behavior and reductions in excitatory synapses
por: Hughes, Brandon W, et al.
Publicado: (2023)

Optimal learning with excitatory and inhibitory synapses
por: Ingrosso, Alessandro
Publicado: (2020)

Differential nanoscale organization of excitatory synapses onto excitatory vs inhibitory neurons
por: Dharmasri, Poorna A., et al.
Publicado: (2023)

Molecular Dissection of Neurobeachin Function at Excitatory Synapses
por: Repetto, Daniele, et al.
Publicado: (2018)

Extracellular Metalloproteinases in the Plasticity of Excitatory and Inhibitory Synapses
por: Wiera, Grzegorz, et al.
Publicado: (2021)

411 Essential role for the neurodevelopmental disorder-linked gene, MEF2C, in inhibitory neuron function and neurotypical behaviors
por: Cho, Yongjoo (Jennifer), et al.
Publicado: (2022)

Remodeling and Tenacity of Inhibitory Synapses: Relationships with Network Activity and Neighboring Excitatory Synapses
por: Rubinski, Anna, et al.
Publicado: (2015)

In Vivo Analysis of MEF2 Transcription Factors in Synapse Regulation and Neuronal Survival
por: Akhtar, M. Waseem, et al.
Publicado: (2012)

Regulation of Excitatory Synapses and Fearful Memories by Stress Hormones
por: Krugers, Harm J., et al.
Publicado: (2011)

The role of dendritic inhibition in shaping the plasticity of excitatory synapses
por: Bar-Ilan, Lital, et al.
Publicado: (2013)

Ultrastructural characterization of GABAergic and excitatory synapses in the inferior colliculus
por: Nakamoto, Kyle T., et al.
Publicado: (2014)

Slitrk1 is localized to excitatory synapses and promotes their development
por: Beaubien, François, et al.
Publicado: (2016)

Integrated plasticity at inhibitory and excitatory synapses in the cerebellar circuit
por: Mapelli, Lisa, et al.
Publicado: (2015)

Glial Contribution to Excitatory and Inhibitory Synapse Loss in Neurodegeneration
por: Henstridge, Christopher M., et al.
Publicado: (2019)

Stability and learning in excitatory synapses by nonlinear inhibitory plasticity
por: Miehl, Christoph, et al.
Publicado: (2022)

FGF22 promotes generation of ribbon synapses through downregulating MEF2D
por: Li, Shuna, et al.
Publicado: (2020)

Age-dependent regulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses by leptin
por: McGregor, Gemma, et al.
Publicado: (2018)

Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D
por: Chang, Chia-Wei, et al.
Publicado: (2017)

Narp regulates homeostatic scaling of excitatory synapses on Parvalbumin interneurons
por: Chang, Michael C., et al.
Publicado: (2010)

INEX – A binary neuronal model with inhibitory and excitatory synapses
por: Lenk, Kerstin, et al.
Publicado: (2011)

N-Cofilin Can Compensate for the Loss of ADF in Excitatory Synapses
por: Görlich, Andreas, et al.
Publicado: (2011)

Neuroligin-1 Loss Is Associated with Reduced Tenacity of Excitatory Synapses
por: Zeidan, Adel, et al.
Publicado: (2012)

Bassoon Speeds Vesicle Reloading at a Central Excitatory Synapse
por: Hallermann, Stefan, et al.
Publicado: (2010)

Inhibition promotes long-term potentiation at cerebellar excitatory synapses
por: Binda, F., et al.
Publicado: (2016)

Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons
por: Müller, Thomas, et al.
Publicado: (2018)

Stargazin Dephosphorylation Mediates Homeostatic Synaptic Downscaling of Excitatory Synapses
por: Louros, Susana R., et al.
Publicado: (2018)

Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses
por: Catsburg, Lisa AE, et al.
Publicado: (2022)

Regulation of hippocampal excitatory synapses by the Zdhhc5 palmitoyl acyltransferase
por: Shimell, Jordan J., et al.
Publicado: (2021)

Postsynaptic Proteins at Excitatory Synapses in the Brain—Relationship with Depressive Disorders
por: Samojedny, Sylwia, et al.
Publicado: (2022)

Genetic Controls Balancing Excitatory and Inhibitory Synaptogenesis in Neurodevelopmental Disorder Models
por: Gatto, Cheryl L., et al.
Publicado: (2010)

New players tip the scales in the balance between excitatory and inhibitory synapses
por: Levinson, Joshua N, et al.
Publicado: (2005)

Preserved Morphology and Physiology of Excitatory Synapses in Profilin1-Deficient Mice
por: Görlich, Andreas, et al.
Publicado: (2012)

TSPAN7: A new player in excitatory synapse maturation and function
por: Bassani, Silvia, et al.
Publicado: (2012)

Specific synapses develop preferentially among sister excitatory neurons in the neocortex
por: Yu, Yong-Chun, et al.
Publicado: (2009)

Spatial Distribution of Excitatory Synapses on the Dendrites of Ganglion Cells in the Mouse Retina
por: Chen, Yin-Peng, et al.
Publicado: (2014)

Excitatory transmission at thalamo–striatal synapses mediates susceptibility to social stress
por: Christoffel, Daniel J., et al.
Publicado: (2015)

The autism/neuroprotection-linked ADNP/NAP regulate the excitatory glutamatergic synapse
por: Sragovich, Shlomo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ao866vfva3lqb6vbof7tq1bpd7