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C. elegans GLP-1/Notch activates transcription in a probability gradient across the germline stem cell pool

C. elegans Notch signaling maintains a pool of germline stem cells within their single-celled mesenchymal niche. Here we investigate the Notch transcriptional response in germline stem cells using single-molecule fluorescence in situ hybridization coupled with automated, high-throughput quantitation...

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Detalles Bibliográficos
Autores principales:	Lee, ChangHwan, Sorensen, Erika B, Lynch, Tina R, Kimble, Judith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094854/ https://www.ncbi.nlm.nih.gov/pubmed/27705743 http://dx.doi.org/10.7554/eLife.18370

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