Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation and apoptosis in diabetic cardiomyopathy

Diabetic cardiomyopathy (DCM) is characterized by structural alterations such as cardiomyocyte hypertrophy, necrosis and focal fibrosis. Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme which can be activated by DNA damage and plays a critical role in various diseases. We hypothesized that...

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Detalles Bibliográficos
Autores principales: Qin, Wei-dong, Liu, Guo-liang, Wang, Juan, Wang, Hao, Zhang, Jian-ning, Zhang, Fan, Ma, Yang, Ji, Xin-ying, Li, Chen, Zhang, Ming-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094949/
https://www.ncbi.nlm.nih.gov/pubmed/27027354
http://dx.doi.org/10.18632/oncotarget.8343

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