Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines

Previous studies have shown that the bone marrow micro-environment supports the myeloproliferative neoplasms (MPN) phenotype including via the production of cytokines that can induce resistance to frontline MPN therapies. However, the mechanisms by which this occurs are poorly understood. Moreover,...

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Detalles Bibliográficos
Autores principales: Kobayashi, Susumu S., Vali, Shireen, Kumar, Ansu, Singh, Neeraj, Abbasi, Taher, Sayeski, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094977/
https://www.ncbi.nlm.nih.gov/pubmed/27056884
http://dx.doi.org/10.18632/oncotarget.8540

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