Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema

The glutamate transporter xCT (SCL7a11, system Xc-, SXC) is an emerging key player in glutamate/cysteine/glutathione homeostasis in the brain and in cancer. xCT expression correlates with the grade of malignancy. Here, we report on the use of the U.S. Food and Drug Administration and EMA-approved xC...

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Detalles Bibliográficos
Autores principales: Sehm, Tina, Fan, Zheng, Ghoochani, Ali, Rauh, Manfred, Engelhorn, Tobias, Minakaki, Georgia, Dörfler, Arnd, Klucken, Jochen, Buchfelder, Michael, Eyüpoglu, Ilker Y., Savaskan, Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094980/
https://www.ncbi.nlm.nih.gov/pubmed/27074570
http://dx.doi.org/10.18632/oncotarget.8651

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