Identification of a novel partner gene, KIAA1217, fused to RET: Functional characterization and inhibitor sensitivity of two isoforms in lung adenocarcinoma

REarranged during Transfection (RET) fusion genes are detected in approximately 1% of lung adenocarcinomas and known primarily as oncogenic driver factors. Here, we found a novel RET fusion gene, KIAA1217-RET, and examined the functional differences of RET51 and RET9 protein, fused with KIAA1217 in...

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Detalles Bibliográficos
Autores principales: Lee, Mi-Sook, Kim, Ryong Nam, I, Hoseok, Oh, Doo-Yi, Song, Ji-Young, Noh, Ka-Won, Kim, Yu-Jin, Yang, Jung Wook, Lira, Maruja E., Lee, Chang Hun, Lee, Min Ki, Kim, Yeoung Dae, Mao, Mao, Han, Joungho, Kim, Jhingook, Choi, Yoon-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094986/
https://www.ncbi.nlm.nih.gov/pubmed/27150058
http://dx.doi.org/10.18632/oncotarget.9137

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