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Co-inhibition of EGFR and IGF1R synergistically impacts therapeutically on adrenocortical carcinoma

PURPOSE: Adrenocortical carcinoma (ACC) is a rare tumor with very poor prognosis and no effective treatment. The aim of this study was to explore a novel therapy co-targeting EGFR and IGF1R in vitro and vivo. METHODS: The expression of EGFR and IGF1R were evaluated in a series of adrenocortical tumo...

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Detalles Bibliográficos
Autores principales:	Xu, Lieyu, Qi, Yicheng, Xu, Yunze, Lian, Jianpo, Wang, Xiaojing, Ning, Guang, Wang, Weiqing, Zhu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094996/ https://www.ncbi.nlm.nih.gov/pubmed/27105537 http://dx.doi.org/10.18632/oncotarget.8827

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