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Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)

BACKGROUND: Non-small-cell lung cancer (NSCLC) patients with activating epidermal growth factor receptor (EGFR) mutations may exhibit primary resistance to EGFR tyrosine kinase inhibitor (TKI). We aimed to examine genomic alterations associated with de novo resistance to gefitinib in a prospective s...

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Detalles Bibliográficos
Autores principales: Lim, Sun Min, Kim, Hye Ryun, Cho, Eun Kyung, Min, Young Joo, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Cho, Byoung Chul, Lee, Ji-Hyun, Jeong, Hye Cheol, Kim, Eun Kyung, Kim, Joo-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095002/
https://www.ncbi.nlm.nih.gov/pubmed/27121209
http://dx.doi.org/10.18632/oncotarget.8904

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