Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer

Telomeric dysfunction is linked to colorectal cancer (CRC) initiation. However, the relationship of normal tissue and tumor telomere lengths with CRC progression, molecular features and prognosis is unclear. Here, we measured relative telomere length (RTL) by real-time quantitative PCR in 90 adenoma...

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Detalles Bibliográficos
Autores principales: Suraweera, Nirosha, Mouradov, Dmitri, Li, Shan, Jorissen, Robert N., Hampson, Debbie, Ghosh, Anil, Sengupta, Neel, Thaha, Mohamed, Ahmed, Shafi, Kirwan, Michael, Aleva, Floor, Propper, David, Feakins, Roger M., Vulliamy, Tom, Elwood, Ngaire J., Tian, Pei, Ward, Robyn L., Hawkins, Nicholas J., Xu, Zheng-Zhou, Molloy, Peter L., Jones, Ian T., Croxford, Matthew, Gibbs, Peter, Silver, Andrew, Sieber, Oliver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095014/
https://www.ncbi.nlm.nih.gov/pubmed/27167335
http://dx.doi.org/10.18632/oncotarget.9015

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