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Genetic alteration profiling of patients with resected squamous cell lung carcinomas

In this study, we analyzed the genetic profiles of squamous cell lung carcinoma (SqCLC) to identify potential therapeutic targets. Approximately 2,800 COSMIC mutations from 50 genes were determined by next-generation sequencing. Amplification/deletion of SOX2, CDKN2A, PTEN, FGFR1, EGFR, CCND1, HER2...

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Detalles Bibliográficos
Autores principales: Tao, Dan, Han, Xiaohong, Zhang, Ningning, Lin, Dongmei, Wu, Di, Zhu, Xinxin, Song, Wenya, Shi, Yuankai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095023/
https://www.ncbi.nlm.nih.gov/pubmed/27145277
http://dx.doi.org/10.18632/oncotarget.9096