RMEL3, a novel BRAF(V600E)-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma

Previous work identified RMEL3 as a lncRNA with enriched expression in melanoma. Analysis of The Cancer Genome Atlas (TCGA) data confirmed RMEL3 enriched expression in melanoma and demonstrated its association with the presence of BRAF(V600E). RMEL3 siRNA-mediated silencing markedly reduced (95%) co...

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Detalles Bibliográficos
Autores principales: Goedert, Lucas, Pereira, Cristiano G., Roszik, Jason, Plaça, Jessica R., Cardoso, Cibele, Chen, Guo, Deng, Wanleng, Yennu-Nanda, Vashisht Gopal, Silva, Wilson A., Davies, Michael A., Espreafico, Enilza M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095033/
https://www.ncbi.nlm.nih.gov/pubmed/27167340
http://dx.doi.org/10.18632/oncotarget.9164

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