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Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification

Pancreatic stellate cells (PSC), a prominent stromal cell, contribute to the progression of pancreatic ductal adenocarcinoma (PDAC). We aim to investigate the mechanisms by which PSC promote cell proliferation in PDAC cell lines, BxPC-3 and AsPC-1. PSC-conditioned media (PSC-CM) induced proliferatio...

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Detalles Bibliográficos
Autores principales:	Wu, Yuan Seng, Looi, Chung Yeng, Subramaniam, Kavita S., Masamune, Atsushi, Chung, Ivy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095034/ https://www.ncbi.nlm.nih.gov/pubmed/27167341 http://dx.doi.org/10.18632/oncotarget.9165

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